Protective effects of arbutin against doxorubicin-induced cardiac damage

Doxorubicin treatment in vivo causes cytochrome C release and cardiomyocyte apoptosis, as well as increased mitochondrial efficiency, superoxide dismutase activity, and Bcl-2:Bax ratio.

April C. Childs, Sharon Phaneuf, Amie J. Dirks et al. · PubMed · 2002 · 452 citations

Medicine, Cardiology, Pharmacology +7

Protective effect of lycopene on adriamycin-induced cardiotoxicity and nephrotoxicity

Seval Yılmaz, Ahmet Ateşşahín, Engin Şahna et al. · Toxicology · 2005 · 267 citations

Medicine, Medicinal Chemistry, Pharmacology +12

The Protective Effects of Silymarin against Doxorubicin-Induced Cardiotoxicity and Hepatotoxicity in Rats

Aleksandar Rašković, Nebojša Stilinović, Jovanka Kolarović et al. · Molecules · 2011 · 171 citations · Full text

Pharmacy, Pharmacology, Toxicology +16

Moderate endurance training prevents doxorubicin-induced in vivo mitochondriopathy and reduces the development of cardiac apoptosis

António Ascensão, José Magalhães, José M. C. Soares et al. · American Journal of Physiology-Heart and Circulatory Physiology · 2005 · 162 citations

Life Sciences, Biochemistry, Physiology +17

Curcumin ameliorates doxorubicin‐induced cardiotoxicity by abrogation of inflammation, apoptosis, oxidative DNA damage, and protein oxidation in rats

Fulya Benzer, Fatih Mehmet Kandemır, Mustafa Özkaraca et al. · Journal of Biochemical and Molecular Toxicology · 2018 · 161 citations

Medicine, Pharmacology, Toxicology +16