Transglutaminase 3 regulates cutaneous squamous carcinoma differentiation and inhibits progression via PI3K-AKT signaling pathway-mediated Keratin 14 degradation

Dwarfism, impaired skin development, skeletal muscle atrophy, delayed bone development, and impeded adipogenesis in mice lacking Akt1 and Akt2

Xiao-ding Peng, Pei-Zhang Xu, Mei-Ling Chen et al. · Genes & Development · 2003 · 820 citations · Full text

Effects of Deguelin on the Phosphatidylinositol 3-Kinase/Akt Pathway and Apoptosis in Premalignant Human Bronchial Epithelial Cells

Kyung‐Hee Chun, Jerome W. Kosmeder, Shi‐Yong Sun et al. · JNCI Journal of the National Cancer Institute · 2003 · 257 citations

Phosphoinositide 3-Kinase Signaling to Akt Promotes Keratinocyte Differentiation Versus Death

Enzo Calautti, Jian Li, Stefania Saoncella et al. · Journal of Biological Chemistry · 2005 · 216 citations · Full text

Skin Development, Phosphoinositide 3-Kinase, Signal Transduction +13

Increased expression of lncRNA CASC9 promotes tumor progression by suppressing autophagy-mediated cell apoptosis via the AKT/mTOR pathway in oral squamous cell carcinoma

Yixin Yang, Dan Chen, Huan Liu et al. · Cell Death and Disease · 2019 · 187 citations · Full text

Apoptosis, Cell Death, Cancer Biology +16

circPARD3 drives malignant progression and chemoresistance of laryngeal squamous cell carcinoma by inhibiting autophagy through the PRKCI-Akt-mTOR pathway

Wei Gao, Huina Guo, Min Niu et al. · Molecular Cancer · 2020 · 172 citations · Full text