Concepedia

Identification of chalcone analogues as anti-inflammatory agents through the regulation of NF-κB and JNK activation

Die Zhang, Wenping Wang, Huiping Ou, Jinhua Ning, Yingxun Zhou, Ke Jin, Anguo Hou, Linyun Chen, Li Peng, Yunshu Ma,

RSC Medicinal Chemistry · 2024 · 11 citations · 19 references

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Abstract

To develop new anti-inflammatory agents with improved pharmaceutical profiles, a series of chalcone analogues were designed and synthesized. The figure was drawn by Figdraw (http://www.figdraw.com).

References

19

Evaluation and Discovery of Novel Synthetic Chalcone Derivatives as Anti-Inflammatory Agents

Jianzhang Wu, Jianling Li, Yuepiao Cai et al. · Journal of Medicinal Chemistry · 2011 · 221 citations

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Synthesis and biological evaluation of new imidazo[2,1-b][1,3,4]thiadiazole-benzimidazole derivatives

Jurupula Ramprasad, Nagabhushana Nayak, Udayakumar Dalimba et al. · European Journal of Medicinal Chemistry · 2015 · 99 citations

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Synthesis and cytotoxicity of epoxide and pyrazole analogs of the combretastatins

Regan M. LeBlanc, John Dickson, Toni Brown et al. · Bioorganic & Medicinal Chemistry · 2005 · 88 citations

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Attenuation of LPS-induced acute lung injury by continentalic acid in rodents through inhibition of inflammatory mediators correlates with increased Nrf2 protein expression

Hassan Ali, Ashraf Ullah Khan, Jawad Ali et al. · BMC Pharmacology and Toxicology · 2020 · 72 citations · Full text

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Artocarpus lakoocha Extract Inhibits LPS-Induced Inflammatory Response in RAW 264.7 Macrophage Cells

Phateep Hankittichai, Pensiri Buacheen, Pornsiri Pitchakarn et al. · International Journal of Molecular Sciences · 2020 · 61 citations · Full text

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