Synthesis, biological evaluation and molecular docking studies of new pyrimidine derivatives as potent dual EGFR/HDAC inhibitors

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

Christopher A. Lipinski, Franco Lombardo, Beryl W. Dominy et al. · Advanced Drug Delivery Reviews · 2012 · 3.7K citations

Pharmacy, Pharmacokinetics, Pharmacology +16

Revisiting the General Solubility Equation: <i>In Silico</i> Prediction of Aqueous Solubility Incorporating the Effect of Topographical Polar Surface Area

Jogoth Ali, Patrick Camilleri, Marc B. Brown et al. · Journal of Chemical Information and Modeling · 2011 · 289 citations

Pharmacy, Chemistry, Computational Chemistry +15

Global challenges in breast cancer detection and treatment

Carlos H. Barrios · The Breast · 2022 · 270 citations · Full text

Public Health, Health Policy, Health Systems +16

Revisiting Nucleophilic Substitution Reactions:  Microwave-Assisted Synthesis of Azides, Thiocyanates, and Sulfones in an Aqueous Medium

Yuhong Ju, Dalip Kumar, Rajender S. Varma · The Journal of Organic Chemistry · 2006 · 204 citations

Natural Sciences, Chemistry, Catalysis +15

Sulfur-Nitrogen Heterocycles

Molecules · 2005 · 148 citations · Full text

Natural Sciences, Chemistry, Organic Chemistry +9