Concepedia

Highly stereoselective α-glycosylation with GalN <sub>3</sub> donors enabled collective synthesis of mucin-related tumor associated carbohydrate antigens

Kunxiu Shou, Yunqin Zhang, Yujie Ji, Bin Liu, Qingli Zhou, Qiang Tan, Fuying Li, Xiufang Wang, Gang Lü, Guozhi Xiao

Chemical Science · 2024 · 32 citations · 67 references

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Concepts

Abstract

Collective synthesis of mucin-related tumor associated carbohydrate antigens has been achieved via this new α-glycosylation method with GalN 3 donors, which features mild conditions, broad substrate scope, high yields and stereoselectivities.

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