Pancreas-directed AAV8 <i>-hSPINK1</i> gene therapy safely and effectively protects against pancreatitis in mice - Concepedia

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Pancreas-directed AAV8 <i>-hSPINK1</i> gene therapy safely and effectively protects against pancreatitis in mice

31

Citations

32

References

2024

Year

Yuan‐Chen Wang, Xiao‐Tong Mao, Chang Sun, Yahui Wang, Yizhou Zheng, Si-Huai Xiong, Muyun Liu, Sheng-Han Mao, Qiwen Wang, Guo-Xiu Ma,

Abstract

One-time injection of AAV8<i>-hSPINK1</i> safely targets the pancreas with high transduction efficiency and effectively ameliorates pancreatitis phenotypes in mice. This approach is promising for the prevention and treatment of CP.

References

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