Concepedia

Clonogenic assay and computational modeling using real cell images to study physical enhancement and cellular sensitization induced by metal nanoparticles under MV and kV X-ray irradiation

Rodrigo Hernández Millares, Chaewon Bae, Seokjin Kim, Tae‐Wan Kim, So‐Yeon Park, Kangwon Lee, Sung‐Joon Ye

Nanoscale · 2024 · 10 citations · 45 references

DOIFull text

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Concepts

Abstract

radiation through mechanisms akin to ferroptosis inducers, not exclusively relying on a physical dose enhancement. Their own contributions to survival fractions were successfully integrated into computational modeling.

References

45

Clonogenic assay of cells in vitro

Nicolaas A.P. Franken, Hans M. Rodermond, Jan Stap et al. · Nature Protocols · 2006 · 4.2K citations

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AAPM's TG‐51 protocol for clinical reference dosimetry of high‐energy photon and electron beams

Peter R. Almond, Peter J. Biggs, Bert M. Coursey et al. · Medical Physics · 1999 · 1.7K citations · Full text

, , +16

The use of gold nanoparticles to enhance radiotherapy in mice

James F. Hainfeld, Daniel N. Slatkin, Henry M. Smilowitz · Physics in Medicine and Biology · 2004 · 1.6K citations

, , +17

The role of ferroptosis in ionizing radiation-induced cell death and tumor suppression

Guang Lei, Yilei Zhang, Pranavi Koppula et al. · Cell Research · 2020 · 1.3K citations · Full text

, , +14

TOPAS: An innovative proton Monte Carlo platform for research and clinical applications

Joseph Perl, Jae‐Gook Shin, J. Schümann et al. · Medical Physics · 2012 · 1.1K citations

, , +17