Concepedia

Unraveling the role of low‐density lipoprotein‐related genes in lung adenocarcinoma: Insights into tumor microenvironment and clinical prognosis

Pengpeng Zhang, Xinyi Wu, Dingli Wang, Mengzhe Zhang, Bin Zhang, Zhenfa Zhang

Environmental Toxicology · 2024 · 24 citations · 47 references

DOI

Abstract

This study elucidates the significance of LRGs within the TME and introduces an LAS for prognostication in LUAD patients. Our findings accentuate putative therapeutic targets and elucidate the clinical ramifications of LAS deployment.

References

47

Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries

Hyuna Sung, Jacques Ferlay, Rebecca L. Siegel et al. · CA A Cancer Journal for Clinicians · 2021 · 109.5K citations · Full text

Inferring tumour purity and stromal and immune cell admixture from expression data

Kosuke Yoshihara, Maria Shahmoradgoli, Emmanuel Martínez et al. · Nature Communications · 2013 · 10.4K citations · Full text

Inference and analysis of cell-cell communication using CellChat

Suoqin Jin, Christian F. Guerrero‐Juarez, Lihua Zhang et al. · Nature Communications · 2021 · 7.5K citations · Full text

Maftools: efficient and comprehensive analysis of somatic variants in cancer

Anand Mayakonda, De‐Chen Lin, Yassen Assenov et al. · Genome Research · 2018 · 5.2K citations · Full text

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Atezolizumab versus docetaxel in patients with previously treated non-small-cell lung cancer (OAK): a phase 3, open-label, multicentre randomised controlled trial

Achim Rittmeyer, Fabrice Barlési, Daniel Waterkamp et al. · The Lancet · 2016 · 4.7K citations · Full text

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