Neurobiological basis of emergence from anesthesia

Sites of alcohol and volatile anaesthetic action on GABAA and glycine receptors

S. John Mihic, Qing Ye, Marilee J. Wick et al. · Nature · 1997 · 1.2K citations

Medicine, Neuroscience, Pharmacology +14

Nitrous oxide (laughing gas) is an NMDA antagonist, neuroprotectant and neurotoxin

Vesna Jevtović‐Todorović, S. M. Todorovć, Steven Mennerick et al. · Nature Medicine · 1998 · 679 citations

Life Sciences, Neuroscience, Pharmacology +14

Inhalational anesthetics activate two-pore-domain background K+ channels

Amanda Patel, Éric Honoré, Florian Lesage et al. · Nature Neuroscience · 1999 · 644 citations

Medicine, Anesthesiology, Pharmacology +12

Do general anaesthetics act by competitive binding to specific receptors?

Nicholas P. Franks, W.R. Lieb · Nature · 1984 · 576 citations

Medicine, Anesthesiology, Pharmacology +16

The sedative component of anesthesia is mediated by GABAA receptors in an endogenous sleep pathway

Laura E. Nelson, Tian‐Zhi Guo, Jun Lu et al. · Nature Neuroscience · 2002 · 572 citations

Medicine, Neuroscience, Pharmacology +15