Protein-assisted synthesis of chitosan-coated minicells enhance dendritic cell recruitment for therapeutic immunomodulation within pulmonary tumors

Principles of nanoparticle design for overcoming biological barriers to drug delivery

Elvin Blanco, Haifa Shen, Mauro Ferrari · Nature Biotechnology · 2015 · 6.7K citations · Full text

Pharmacy, Biomedical Engineering, Pharmaceutics +16

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

Hiroki Ishikawa, Glen N. Barber · Nature · 2008 · 3.5K citations · Full text

Life Sciences, Cell Biology, Immunology +12

Safety and activity of microRNA-loaded minicells in patients with recurrent malignant pleural mesothelioma: a first-in-man, phase 1, open-label, dose-escalation study

Nico van Zandwijk, Nick Pavlakis, Steven Kao et al. · The Lancet Oncology · 2017 · 709 citations

Medicine, Oncology, Pharmacology +15

The Vaccine Adjuvant Chitosan Promotes Cellular Immunity via DNA Sensor cGAS-STING-Dependent Induction of Type I Interferons

Elizabeth C. Carroll, Lei Jin, Andrés Mori et al. · Immunity · 2016 · 585 citations · Full text

Life Sciences, Immunology, Molecular Biology +12

Immunotherapy with engineered bacteria by targeting the STING pathway for anti-tumor immunity

Daniel S. Leventhal, Anna Sokolovska, Ning Li et al. · Nature Communications · 2020 · 436 citations · Full text

Life Sciences, Biotechnology, Immunology +17