Concepedia

Targeting blood brain barrier—Remote ischemic conditioning alleviates cognitive impairment in female <scp>APP</scp> / <scp>PS1</scp> rats

Yuxuan Ma, Wuxiang Sun, Jing Bai, Fujia Gao, Haoran Ma, Huiyu Liu, Jiewei Hu, Chao Xu, Xin Zhang, Zixuan Liu,

CNS Neuroscience & Therapeutics · 2024 · 12 citations · 71 references

DOIFull text

Open access

Abstract

Chronic RIC intervention exerts vascular and neuroprotective roles, suggesting that RIC could be a promising therapeutic strategy targeting the BBB and NVU during AD development.

References

71

Neurotoxic reactive astrocytes are induced by activated microglia

Shane A. Liddelow, Kevin A. Guttenplan, Laura Clarke et al. · Nature · 2017 · 7.6K citations · Full text

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The use of the elevated plus maze as an assay of anxiety-related behavior in rodents

Alicia A. Walf, Cheryl A. Frye · Nature Protocols · 2007 · 2.9K citations · Full text

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2022 Alzheimer's disease facts and figures

Alzheimer s & Dementia · 2022 · 2.3K citations

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Human hippocampal neurogenesis drops sharply in children to undetectable levels in adults

Shawn F. Sorrells, Mercedes F. Paredes, Arantxa Cebrián‐Silla et al. · Nature · 2018 · 1.4K citations · Full text

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Two Randomized Phase 3 Studies of Aducanumab in Early Alzheimer's Disease

Samantha Budd Haeberlein, Paul Aisen, Frederik Barkhof et al. · The Journal of Prevention of Alzheimer s Disease · 2022 · 1.2K citations · Full text