Concepedia

Dexamethasone upregulates macrophage PIEZO1 via SGK1, suppressing inflammation and increasing ROS and apoptosis

Hailin Liu, Lian Zhou, Xifeng Wang, Qingcui Zheng, Fenfang Zhan, Lanqian Zhou, Yao Dong, Yanhong Xiong, Pengcheng Yi, Xu Guohai,

Biochemical Pharmacology · 2024 · 42 citations · 44 references

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44

Dexamethasone in Hospitalized Patients with Covid-19

New England Journal of Medicine · 2020 · 10.1K citations · Full text

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Immunodesign of experimental sepsis by cecal ligation and puncture

Daniel Rittirsch, Markus Huber‐Lang, Michael A. Flierl et al. · Nature Protocols · 2008 · 2.2K citations · Full text

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Effect of Dexamethasone on Days Alive and Ventilator-Free in Patients With Moderate or Severe Acute Respiratory Distress Syndrome and COVID-19

Bruno Martins Tomazini, Israel Silva Maia, Alexandre Biasi Cavalcanti et al. · JAMA · 2020 · 1.3K citations · Full text

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Mechanically activated ion channel Piezo1 modulates macrophage polarization and stiffness sensing

Hamza Atcha, Amit Jairaman, Jesse R. Holt et al. · Nature Communications · 2021 · 579 citations · Full text

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TLR4 signalling via Piezo1 engages and enhances the macrophage mediated host response during bacterial infection

Jing Geng, Yiran Shi, Jinjia Zhang et al. · Nature Communications · 2021 · 267 citations · Full text

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