Concepedia

Deubiquitinase OTUD6a drives cardiac inflammation and hypertrophy by deubiquitination of STING

Zimin Fang, Jibo Han, Liming Lin, Bozhi Ye, Xuefeng Qu, Yu Zhang, Ying‐Yong Zhao, Diyun Xu, Wante Lin, Sirui Shen,

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 2024 · 17 citations · 17 references

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17

cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING

Andrea Ablasser, Marion Goldeck, Taner Cavlar et al. · Nature · 2013 · 1.6K citations · Full text

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USP13 negatively regulates antiviral responses by deubiquitinating STING

He Sun, Qiang Zhang, Yingying Jing et al. · Nature Communications · 2017 · 196 citations · Full text

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STING is an essential regulator of heart inflammation and fibrosis in mice with pathological cardiac hypertrophy via endoplasmic reticulum (ER) stress

Yan Zhang, Wenzhong Chen, Yan Wang · Biomedicine & Pharmacotherapy · 2020 · 177 citations · Full text

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USP18 recruits USP20 to promote innate antiviral response through deubiquitinating STING/MITA

Man Zhang, Meng‐Xin Zhang, Qiang Zhang et al. · Cell Research · 2016 · 160 citations · Full text

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USP25 Ameliorates Pathological Cardiac Hypertrophy by Stabilizing SERCA2a in Cardiomyocytes

Bozhi Ye, Hao Zhou, Yanghao Chen et al. · Circulation Research · 2023 · 120 citations · Full text

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