Differential <i>in vitro</i> susceptibility to ampicillin/ceftriaxone combination therapy among <i>Enterococcus faecalis</i> infective endocarditis clinical isolates

Abstract

We find evidence for diminished in vitro AC activity among a subset of E. faecalis IE isolates with increased pbp4 expression. These findings suggest that alternate antibiotic combinations against diverse contemporary E. faecalis IE isolates should be evaluated.