Concepedia

Lysosome targeted visible light-induced photo-CORM for simultaneous CO-release and singlet oxygen generation

Upendar Reddy Gandra, Batakrishna Jana, Patrick Hammer, M. Infas H. Mohideen, Ute Neugebauer, Alexander Schiller

Chemical Communications · 2024 · 16 citations · 29 references

DOI

Concepts

Abstract

release, and its good biocompatibility, negligible dark toxicity and specific lysosome targeting make Lyso-CORM a potent candidate for phototherapeutic applications.

References

29

An Emerging Molecular Design Approach to Heavy-Atom-Free Photosensitizers for Enhanced Photodynamic Therapy under Hypoxia

Nguyễn Văn Nghĩa, Sujie Qi, Sangin Kim et al. · Journal of the American Chemical Society · 2019 · 445 citations

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Enrichment-triggered prodrug activation demonstrated through mitochondria-targeted delivery of doxorubicin and carbon monoxide

Yueqin Zheng, Xingyue Ji, Bingchen Yu et al. · Nature Chemistry · 2018 · 313 citations · Full text

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Photocatalytic Superoxide Radical Generator that Induces Pyroptosis in Cancer Cells

Le Yu, Yunjie Xu, Zhongji Pu et al. · Journal of the American Chemical Society · 2022 · 275 citations

, , +15

Design Strategies To Improve the Sensitivity of Photoactive Metal Carbonyl Complexes (photoCORMs) to Visible Light and Their Potential as CO-Donors to Biological Targets

Indranil Chakraborty, Samantha J. Carrington, Pradip K. Mascharak · Accounts of Chemical Research · 2014 · 231 citations

, , +14

A Luminescent and Biocompatible PhotoCORM

Agustin E. Pierri, Alessia Pallaoro, Guang Wu et al. · Journal of the American Chemical Society · 2012 · 213 citations

, , +12