Surgery for advanced adrenal malignant disease: recommendations based on European Society of Endocrine Surgeons consensus meeting

Abstract

ACC is an exceedingly rare tumour, with an estimated incidence of 1-2 per million population per year, and an overall 5-year survival rate of only 30 per cent. The survival rate ranges from 60 to 80 per cent for tumours confined to the adrenal gland, from 35 to 50 per cent for locally advanced disease, and much lower for patients with metastatic disease (below 30 per cent) 3 .