Concepedia

Branched pegylated linker-auristatin to control hydrophobicity for the production of homogeneous minibody-drug conjugate against HER2-positive breast cancer

Emmanuel Douez, Émilie Allard-Vannier, Imène Ait Mohamed Amar, Louis Jolivet, Fanny Boursin, Aurélie Maisonial‐Besset, Tiffany Witkowski, Jean‐Michel Chezal, Cyril Colas, Stéphanie Letast,

Journal of Controlled Release · 2024 · 21 citations · 43 references

DOI

Concepts

References

43

Targeting HER2-Positive Breast Cancer with Trastuzumab-DM1, an Antibody–Cytotoxic Drug Conjugate

Gail D. Lewis Phillips, Guangmin Li, Debra L. Dugger et al. · Cancer Research · 2008 · 1.7K citations

, , +17

ESMO Clinical Practice Guideline for the diagnosis, staging and treatment of patients with metastatic breast cancer

Alessandra Gennari, Fabrice André, Carlos H. Barrios et al. · Annals of Oncology · 2021 · 1.4K citations · Full text

, , +14

Determination of the immunoreactive function of radiolabeled monoclonal antibodies by linear extrapolation to binding at infinite antigen excess

Tore Lindmo, Epie Boven, Frank Cuttitta et al. · Journal of Immunological Methods · 1984 · 937 citations

, , +13

Early breast cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up

Sibylle Loibl, Fabrice André, Thomas Bachelot et al. · Annals of Oncology · 2023 · 844 citations · Full text

, , +13

Reducing hydrophobicity of homogeneous antibody-drug conjugates improves pharmacokinetics and therapeutic index

Robert P. Lyon, Tim D. Bovee, Svetlana O. Doronina et al. · Nature Biotechnology · 2015 · 523 citations

, , +14