Navigating the dementia landscape: Biomarkers and emerging therapies

Picomolar Amyloid-β Positively Modulates Synaptic Plasticity and Memory in Hippocampus

Daniela Puzzo, Lucia Privitera, Elena Leznik et al. · Journal of Neuroscience · 2008 · 716 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Altered bile acid profile associates with cognitive impairment in Alzheimer's disease—An emerging role for gut microbiome

Siamak MahmoudianDehkordi, Matthias Arnold, Kwangsik Nho et al. · Alzheimer s & Dementia · 2018 · 694 citations · Full text

Life Sciences, Microbiology, Neuroscience +17

Alzheimer's disease drug development pipeline: 2021

Jeffrey L. Cummings, Garam Lee, Kate Zhong et al. · Alzheimer s & Dementia Translational Research & Clinical Interventions · 2021 · 533 citations · Full text

Medicine, Neuroscience, Pharmacology +16

β-Amyloid Activates the Mitogen-Activated Protein Kinase Cascade via Hippocampal α7 Nicotinic Acetylcholine Receptors:<i>In Vitro</i>and<i>In Vivo</i>Mechanisms Related to Alzheimer's Disease

Kelly T. Dineley, Marcus A. Westerman, Duy Bui et al. · Journal of Neuroscience · 2001 · 462 citations · Full text

Life Sciences, Neurology, Neuroscience +17

Lecanemab, Aducanumab, and Gantenerumab — Binding Profiles to Different Forms of Amyloid-Beta Might Explain Efficacy and Side Effects in Clinical Trials for Alzheimer's Disease

Linda Söderberg, Malin Johannesson, Patrik Nygren et al. · Neurotherapeutics · 2022 · 413 citations · Full text

Life Sciences, Pharmacology, Dementia +15