Intracellular and extracellular synergistic therapy for restoring macrophage functions via anti-CD47 antibody-conjugated bifunctional nanoparticles in atherosclerosis

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

Peter Duewell, Hajime Kono, Katey J. Rayner et al. · Nature · 2010 · 3.8K citations · Full text

Inflammation, Signal Transduction, Oxysterol +12

CD47-blocking antibodies restore phagocytosis and prevent atherosclerosis

Yoko Kojima, Jens-Peter Volkmer, Kelly M. McKenna et al. · Nature · 2016 · 630 citations · Full text

Immunology, Autoimmunity, Immunotherapy +3

Treatment of atherosclerosis by macrophage-biomimetic nanoparticles via targeted pharmacotherapy and sequestration of proinflammatory cytokines

Gao Cheng, Qiaoxian Huang, Conghui Liu et al. · Nature Communications · 2020 · 586 citations · Full text

Regulating the absorption spectrum of polydopamine

Yuan Zou, Xiaofeng Chen, Peng Yang et al. · Science Advances · 2020 · 458 citations · Full text

Neurotransmitter, Synthetic Photochemistry, Chemistry +17

Disrupting the CD47-SIRPα anti-phagocytic axis by a humanized anti-CD47 antibody is an efficacious treatment for malignant pediatric brain tumors

Sharareh Gholamin, Siddhartha S. Mitra, Abdullah H. Feroze et al. · Science Translational Medicine · 2017 · 413 citations