Tim-3 deficiency aggravates cadmium nephrotoxicity via regulation of NF-κB signaling and mitochondrial damage

Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease

Laurent Monney, Catherine A. Sabatos, Jason L. Gaglia et al. · Nature · 2002 · 1.6K citations

Life Sciences, Cell Biology, Immunology +16

Promotion of Tissue Inflammation by the Immune Receptor Tim-3 Expressed on Innate Immune Cells

Ana C. Anderson, David E. Anderson, Lisa Bregoli et al. · Science · 2007 · 704 citations

Life Sciences, Immunology, Immunoregulation +14

TIM-3 restrains anti-tumour immunity by regulating inflammasome activation

Karen O. Dixon, Marcin Tabaka, Markus A. Schramm et al. · Nature · 2021 · 367 citations · Full text

Medicine, Immunology, Oncology +14

KIM-1–mediated phagocytosis reduces acute injury to the kidney

Li Yang, Craig R. Brooks, Sheng Xiao et al. · Journal of Clinical Investigation · 2015 · 357 citations · Full text

Life Sciences, Pathobiology, Pathology +17

Tim-3 aggravates podocyte injury in diabetic nephropathy by promoting macrophage activation via the NF-κB/TNF-α pathway

Huimin Yang, Tingting Xie, Dengren Li et al. · Molecular Metabolism · 2019 · 187 citations · Full text

Medicine, Immunology, Pathology +17