Photoresponsive metal-organic framework with combined photodynamic therapy and hypoxia-activated chemotherapy for the targeted treatment of rheumatoid arthritis

Locally renewing resident synovial macrophages provide a protective barrier for the joint

Stephan Culemann, Anika Grüneboom, José Ángel Nicolás-Ávila et al. · Nature · 2019 · 613 citations · Full text

Life Sciences, Cell Biology, Immunology +13

Targeted silver nanoparticles for rheumatoid arthritis therapy via macrophage apoptosis and Re-polarization

Yihua Yang, Lina Guo, Zhe Wang et al. · Biomaterials · 2020 · 486 citations

Life Sciences, Immunology, Pharmaceutics +16

Inflammation-Targeted Celastrol Nanodrug Attenuates Collagen-Induced Arthritis through NF-κB and Notch1 Pathways

Lemei An, Zhanrong Li, Liuqi Shi et al. · Nano Letters · 2020 · 210 citations

Medicine, Pharmaceutics, Pharmacology +17

Efficient NIR-II Type-I AIE Photosensitizer for Mitochondria-Targeted Photodynamic Therapy through Synergistic Apoptosis–Ferroptosis

Jiabao Zhuang, Bing Wang, Huan Chen et al. · ACS Nano · 2023 · 201 citations

Medicine, Oncology, Pharmacology +17

Construction of a two-dimensional artificial antioxidase for nanocatalytic rheumatoid arthritis treatment

Bowen Yang, Heliang Yao, Jiacai Yang et al. · Nature Communications · 2022 · 179 citations · Full text

Natural Sciences, Biochemistry, Chemistry +17