Locally renewing resident synovial macrophages provide a protective barrier for the joint

Stephan Culemann, Anika Grüneboom, José Ángel Nicolás-Avila, +29

Nature

InflammationRheumatologyProtective BarrierResident Synovial MacrophagesRheumatoid Disorder +10

Targeting zonulin and intestinal epithelial barrier function to prevent onset of arthritis

Narges Tajik, Michael Frech, Oscar Schulz, +26

Nature Communications

Chronic Inflammatory DiseasesImmunologyZonulin Family PeptideInflammatory ArthritisGut Microbial Dysbiosis +16

Regulation of autoantibody activity by the IL-23–TH17 axis determines the onset of autoimmune disease

René Pfeifle, Tobias Rothe, Natacha Ipseiz, +31

Nature Immunology

ImmunodeficienciesImmunologyImmune RegulationImmune SystemImmune Dysregulation +15

A network of trans-cortical capillaries as mainstay for blood circulation in long bones

Anika Grüneboom, Ibrahim Hawwari, Daniela Weidner, +36

Nature Metabolism

MechanobiologyPhysiologyBlood CirculationLong BonesTrans-cortical Capillaries +6

IL-33-induced metabolic reprogramming controls the differentiation of alternatively activated macrophages and the resolution of inflammation

Maria Faas, Natacha Ipseiz, Jochen A. Ackermann, +23

Immunity

InflammationCytokineAutoimmune DiseaseImmune Cell DevelopmentImmune Regulation +7

JAK inhibition increases bone mass in steady-state conditions and ameliorates pathological bone loss by stimulating osteoblast function

Susanne Adam, Nils Simon, Ulrike Steffen, +12

Science Translational Medicine

Stunning of neutrophils accounts for the anti-inflammatory effects of clodronate liposomes

Stephan Culemann, Katharina Knab, Maximilien Euler, +14

The Journal of Experimental Medicine

InflammationAnti-inflammatoryAutoimmune DiseaseMoph DeficiencyNeutrophils Accounts +12

Glucocorticoid receptor in stromal cells is essential for glucocorticoid-mediated suppression of inflammation in arthritis

Mascha Koenen, Stephan Culemann, Sabine Vettorazzi, +6

Annals of the Rheumatic Diseases

RELMα-expressing macrophages protect against fatal lung damage and reduce parasite burden during helminth infection

Branislav Krljanac, Christoph Schubart, Ronald Naumann, +4

Science Immunology

Eosinophils are not essential for maintenance of murine plasma cells in the bone marrow

Konrad Haberland, Jochen A. Ackermann, Natacha Ipseiz, +7

European Journal of Immunology

Clinical ImmunologyImmunodeficienciesImmunologyImmune RegulationPathology +24