International Journal of Biomedical Science · 2005 · 35 citations · 0 references
MedicineEndocrinologyNutritional SciencesBone MetabolismCancer PreventionMineral MetabolismBone EndocrinologyBone HealthBone Metabolism DisordersMetabolic Bone DiseaseOsteoporosisBone Mineral DensityOsteoporosis In WomenPhytochemicals In Cancer PreventionPolyphenol ChemopreventionPostmenopausal Osteoporosis Treatment
Hormone replacement therapy (HRT) has been used to prevent osteoporosis in postmenopausal women. However, HRT is not for everyone, due to concerns of side effects as well as increased risk of breast and possibly uterine cancer. Therefore, Dietary alternatives are considered, which include Trans-3,5,4'-Trihydroxystilbene (trans-resveratrol), a phytoestrogen naturally found in grapes, peanuts and wine with beneficial effects in both cardioprotective and chemopreventive. The purpose of this study was to evaluate the effects of trans-resveratrol on the bone metabolism in ovariectomized rats.