Spatio-temporal dynamics of microglia phenotype in human and murine cSVD: impact of acute and chronic hypertensive states

A Threshold Selection Method from Gray-Level Histograms

Nobuyuki Otsu · IEEE Transactions on Systems Man and Cybernetics · 1979 · 42.3K citations

Image Analysis, Machine Vision, Engineering +8

Analyzing real-time PCR data by the comparative CT method

Thomas D. Schmittgen, Kenneth J. Livak · Nature Protocols · 2008 · 26K citations

Computed Tomography, Image Analysis, Engineering +8

Staging of brain pathology related to sporadic Parkinson’s disease

Heiko Braak, Kelly Del Tredici, Udo Rüb et al. · Neurobiology of Aging · 2002 · 10.5K citations

Neurodegenerative Diseases, Parkinson Disease, Neurology +6

UMAP: Uniform Manifold Approximation and Projection

Leland McInnes, John Healy, Nathaniel Saul et al. · The Journal of Open Source Software · 2018 · 8.9K citations · Full text

A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease

Hadas Keren‐Shaul, Amit Spinrad, Assaf Weiner et al. · Cell · 2017 · 5.2K citations · Full text

Neurodegenerative Diseases, Alzheimer's Disease, Medicine +10