Concepedia

Sensitive monitoring of NAD(P)H levels within cancer cells using mitochondria-targeted near-infrared cyanine dyes with optimized electron-withdrawing acceptors

Dilka Liyana Arachchige, Sushil K. Dwivedi, M.G.J. Waters, Sophia Jaeger, J. Peters, Daniel R. Tucker, Micaela Geborkoff, Thomas Werner, Rudy L. Luck, Bhaskar Godugu,

Journal of Materials Chemistry B · 2023 · 20 citations · 38 references

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Concepts

Abstract

Probes A and B were developed for NAD(P)H sensing, exhibiting responsive near-infrared emissions with minimal photodamage and effective tissue penetration. Probes C , D , and E showed reduced responsiveness to NAD(P)H.

References

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