Concepedia

Gold catalyzed spirocyclization of 1-ene-4,9- and 3-ene-1,7-diyne esters to azaspiro[4.4]nonenones and azaspiro[4.5]decadienones

Zhen Liu, Mitch Mathiew, Jichao Chen, Xiangdong Yu, Dandan Shang, Javey Khiapeng Tan, Philip Wai Hong Chan, Weidong Rao

Organic Chemistry Frontiers · 2023 · 10 citations · 43 references

DOIFull text

Open access

Concepts

Abstract

A method to prepare a structurally diverse range of spirocyclic cyclopentanes, furans, pyrrolidines and piperidines, which relies on the gold( i )-catalyzed spirocyclization of 1-ene-4,9- and 3-ene-1,7-diyne esters, has been developed.

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