Angewandte Chemie International Edition · 2023 · 27 citations · 64 references
Natural SciencesChemistryCatalysisOrganic ChemistryOrganometallic ChemistryCoordination ChemistryCross-coupling ReactionsHeterocyclic ChemistryOrganic SynthesisOxidative AdditionTransition Metal ChemistryAlkyl Cross-couplingCross-coupling CatalysisPalladium CatalystsPalladium-catalyzed Cross-couplingReductive Cross-couplingTransition-metal-catalyzed Cross-coupling
Abstract We report the first reductive vinylation of alkyl iodides. The reaction uses a vinyl thianthrenium salt, a palladium catalyst, and an alkyl zinc intermediate formed in situ to trap the L n Pd II (vinyl) complex formed after oxidative addition before it undergoes undesired homocoupling to form butadiene.
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