Concepedia

Effect of trimetazidine against ovarian ischemia/reperfusion injury in rat model: A new pathway: JAK2/STAT3.

Tuğba Nurcan Yüksel, Erdem Toktay, Bengül Özdemir, Ayşe Bozkurt

PubMed · 2023 · 10 citations · 64 references

DOIFull text

Open access

Abstract

TMZ treatment protected rats against ovarian ischemia/reperfusion injury by alleviating oxidative stress and inflammatory cascades. These findings may provide a mechanistic basis for using TMZ to treat ovarian ischemia-reperfusion injury.

References

64

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Kenneth J. Livak, Thomas D. Schmittgen · Methods · 2001 · 176.9K citations

, , +12

Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction

Hiroshi Ohkawa, Nobuko Ohishi, Kunio Yagi · Analytical Biochemistry · 1979 · 28.6K citations

, , +10

Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent

J Sedlák · Analytical Biochemistry · 1968 · 7.9K citations

, , +7

Oligomerization and phosphorylation of the Ire1p kinase during intracellular signaling from the endoplasmic reticulum to the nucleus.

Caroline E. Shamu, Peter Walter · The EMBO Journal · 1996 · 1.3K citations · Full text

, , +9

JAK2 and STAT3 activation contributes to neuronal damage following transient focal cerebral ischemia

Irawan Satriotomo, Kellie K. Bowen, Raghu Vemuganti · Journal of Neurochemistry · 2006 · 233 citations