JCO Oncology Practice · 2023 · 13 citations · 32 references
MedicineHealth InformaticsOncologyBehavioral HealthCancer Symptom ManagementPsychotherapyAnxiety DisordersAnxiety ManagementCognitive Behavioral TherapyPsychological Distress ManagementSupportive Care In CancerSymptom ManagementCancer-related Psychological DistressCancer-related Symptom DistressCognitive Behavioral Stress ManagementCognitive Interventions For AnxietyDepression In Advanced CancerDepression SymptomsPatient-reported Outcomes For DepressionPrimary Outcome Analysis
PURPOSE: Patients with cancer often experience elevated levels of distress. This double-blind, randomized controlled trial compared the impact of an app-based version of cognitive behavioral stress management (CBSM) versus a health education sham app on anxiety and depression symptoms. METHODS: Patients with nonmetastatic (stage I-III) cancer who were receiving or recently completed (≤6 months) systemic treatment were recruited nationwide. The primary outcome of change in anxiety symptoms (PROMIS-Anxiety) over 12 weeks and the top secondary outcome of change in depression symptoms (PROMIS-Depression) over 12 weeks were analyzed using mixed-effects modeling with repeated measures (weeks 0, 4, 8, 12). Patient global impressions of change in anxiety and depression were reported at weeks 4, 8, and 12. In addition, self-reported adverse events were collected throughout the study and adjudicated by the site principal investigator. RESULTS: < .001) compared with the control. CONCLUSION: The use of digitized CBSM led to significant improvements in anxiety and depression outcomes compared with the sham app.
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Michael H. Antoni, Jessica M. Lehman, Kristin M. Klibourn et al. · Health Psychology · 2001 · 864 citations
Michael H. Antoni, Jessica M. Lehman, Kristin Kilbourn et al. · Health Psychology · 2001 · 779 citations