C-reactive protein impairs immune response of CD8⁺ T cells via FcγRIIb-p38MAPK-ROS axis in multiple myeloma

Abstract

We found that CRP impaired immune response of CD8⁺ T cells via FcγRIIb-p38MAPK-ROS signaling pathway. The study casted new insights into the role of CRP in anti-myeloma immunity, providing implications for future immunotherapy in MM.