Thromboembolic Complications Following Perioperative Tranexamic Acid Administration

Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial

The Lancet · 2010 · 3.3K citations · Full text

Medicine, Pharmacotherapy, Surgery +16

Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a randomised, placebo-controlled trial

The Lancet · 2019 · 934 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +16

Hyperfibrinolysis, physiologic fibrinolysis, and fibrinolysis shutdown

Hunter B. Moore, Ernest E. Moore, Eduardo Gonzalez et al. · The Journal of Trauma: Injury, Infection, and Critical Care · 2014 · 443 citations

Medicine, Surgery, Hemodynamic Management +16

The why and how our trauma patients die: A prospective Multicenter Western Trauma Association study

Rachael A. Callcut, Lucy Z. Kornblith, Amanda S. Conroy et al. · The Journal of Trauma: Injury, Infection, and Critical Care · 2019 · 234 citations · Full text

Medicine, Emergency Medicine, Surgery +15

Tranexamic acid administration is associated with an increased risk of posttraumatic venous thromboembolism

Sara P. Myers, Matthew Kutcher, Matthew R. Rosengart et al. · The Journal of Trauma: Injury, Infection, and Critical Care · 2018 · 202 citations

Medicine, Emergency Medicine, Perioperative Medicine +17