Concepedia

Safety, tolerability, pharmacokinetics, and immunological activity of dual-combinations and triple-combinations of anti-HIV monoclonal antibodies PGT121, PGDM1400, 10-1074, and VRC07-523LS administered intravenously to HIV-uninfected adults: a phase 1 randomised trial

Magdalena E. Sobieszczyk, Sharon Mannheimer, Carmen A. Paez, Chenchen Yu, Theresa Gamble, Deborah Theodore, Wairimu Chege, Margaret Yacovone, Brett Hanscom, Jack Heptinstall,

The Lancet HIV · 2023 · 31 citations · 24 references

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Concepts

References

24

Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding

Johannes F. Scheid, Hugo Mouquet, Beatrix Ueberheide et al. · Science · 2011 · 1.2K citations · Full text

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Measuring HIV Neutralization in a Luciferase Reporter Gene Assay

David C. Montefiori · Methods in molecular biology · 2009 · 600 citations

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Optimization and validation of the TZM-bl assay for standardized assessments of neutralizing antibodies against HIV-1

Marcella Sarzotti‐Kelsoe, Robert T. Bailer, Miroslawa Bilska et al. · Journal of Immunological Methods · 2013 · 585 citations

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Two Randomized Trials of Neutralizing Antibodies to Prevent HIV-1 Acquisition

Lawrence Corey, Peter B. Gilbert, Michal Juraska et al. · New England Journal of Medicine · 2021 · 539 citations · Full text

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Recombinant HIV envelope trimer selects for quaternary-dependent antibodies targeting the trimer apex

Devin Sok, Marit J. van Gils, Matthias Pauthner et al. · Proceedings of the National Academy of Sciences · 2014 · 393 citations · Full text

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