Theranostics · 2023 · 21 citations · 33 references
Life SciencesCell BiologyOncologyCell Fate SpecificationGene ExpressionMolecular OncologyAnimal Cell CultureCancer TranscriptomicsCellular ReprogrammingLineage TracingInduced Hepatocyte ReprogrammingLentiviral VectorsLineage ReprogrammingLineage Reprogramming EfficiencyReprogramming EfficiencyTranscription Factor ReprogrammingTranscription Factor-mediated ReprogrammingTranscriptional Reprogramming In Cancer
Our findings demonstrate that reprogramming could be a promising method to produce hepatocytes and treat TNBC liver metastasis. And the LOC model could intimate the 3D liver microenvironment and assess the behavior of the reprogrammed TNBC cells.
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