Linezolid Population Pharmacokinetic Model in Plasma and Cerebrospinal Fluid Among Patients With Tuberculosis Meningitis

Abstract

Linezolid was readily detected in CSF despite high-dose rifampicin coadministration. These findings support continued clinical evaluation of linezolid plus high-dose rifampicin for the treatment of TBM in adults. Clinical Trials Registration. ClinicalTrials.gov (NCT03927313).

References

Page 1

	Year	Citations
Research electronic data capture (REDCap)—A metadata-driven methodology and workflow process for providing translational research informatics support Paul A. Harris, Robert Taylor, Robert J. Thielke, Journal of Biomedical Informatics EngineeringData ScienceMetadata ManagementManagementWorkflow Process	2008	48.8K
The REDCap consortium: Building an international community of software platform partners Paul A. Harris, Robert J. Taylor, Brenda L. Minor, Journal of Biomedical Informatics Software MaintenanceEngineeringInternational CommunityOpen-source Software DevelopmentOpen-source Software	2019	22.2K
Prediction of Creatinine Clearance from Serum Creatinine Donald W. Cockcroft, Henry Gault Nephron	1976	15.3K
Quantification of Lean Bodyweight Sarayut Janmahasatian, Stephen B. Duffull, Susan Ash, Clinical Pharmacokinetics ObesityWeight StatusPhysical ActivityKinesiologyBody Composition	2005	879
Perl-speaks-NONMEM (PsN)—a Perl module for NONMEM related programming Lars Lindbom, Jakob Ribbing, E. Niclas Jonsson Computer Methods and Programs in Biomedicine Computational LinguisticsScripting LanguageIntermediate RepresentationPerl ModuleProgramming Language Design	2004	718
Dynamics of brain-derived proteins in cerebrospinal fluid Hansotto Reiber Clinica Chimica Acta NeurophysiologyBrain-derived ProteinsCerebrospinal FluidNeurological FunctionNeurology	2001	504
The global burden of tuberculosis mortality in children: a mathematical modelling study Peter J. Dodd, Courtney M. Yuen, Charalambos Sismanidis, The Lancet Global Health	2017	427
Proteins in cerebrospinal fluid and blood: Barriers, CSF flow rate and source-related dynamics Hansotto Reiber Restorative Neurology and Neuroscience Source-related DynamicsNeurochemical BiomarkersCsf Flow RateBlood/csf Barrier FunctionCerebral Vascular Regulation	2003	344
Risk factors for infections related to external ventricular drainage Daphna Hoefnagel, Rúben Dammers, Mariël P. Ter Laak‐Poort, Acta Neurochirurgica Healthcare-associated InfectionInfective EndocarditisCardiologyRisk FactorsInfection Control	2008	276
Statistical Adjustment of Data F. H. Harries Annals of the Entomological Society of America Entomological SocietyInsect ConservationEvolutionary BiologyEntomologyData Preparation	1944	181

Page 1