Concepedia

Knock-down of IGFBP2 ameliorates lung fibrosis and inflammation in rats with severe pneumonia through STAT3 pathway

Yuyu Wang, Jianjiang Huang, Fang Zhang, K. M. Shen, Bin Qiu

Growth Factors · 2023 · 19 citations · 14 references

DOI

Abstract

Knock-down of IGFBP2 ameliorated lung injury in SP rats, inhibited inflammation and pulmonary fibrosis, and promoted M2-type transformation of AMs by activating the STAT3 pathway.

References

14

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Alveolar macrophage-derived microvesicles mediate acute lung injury

Sanooj Soni, Michael R. Wilson, Kieran P. O’Dea et al. · Thorax · 2016 · 218 citations · Full text

Sputum biomarkers in IPF: Evidence for raised gene expression and protein level of IGFBP-2, IL-8 and MMP-7

Julien Guiot, M. Henket, J L Corhay et al. · PLoS ONE · 2017 · 88 citations · Full text

IGFBP2 promotes tumor progression by inducing alternative polarization of macrophages in pancreatic ductal adenocarcinoma through the STAT3 pathway

Longhao Sun, Xuebin Zhang, Qianqian Song et al. · Cancer Letters · 2020 · 85 citations · Full text

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IGFBP2 regulates PD-L1 expression by activating the EGFR-STAT3 signaling pathway in malignant melanoma

Ting Li, Chao Zhang, Gang Zhao et al. · Cancer Letters · 2020 · 82 citations · Full text

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