Concepedia

Melatonin inhibits fibroblast cell functions and hypertrophic scar formation by enhancing autophagy through the MT2 receptor-inhibited PI3K/Akt /mTOR signaling

Yunxian Dong, Xiaoling Cao, Jinsheng Huang, Zhicheng Hu, Chufen Chen, Miao Chen, Long Qian, Zhongye Xu, Dongming Lv, Yanchao Rong,

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 2023 · 28 citations · 30 references

DOI

Concepts

References

30

Autophagy fights disease through cellular self-digestion

Noboru Mizushima, Beth Levine, Ana María Cuervo et al. · Nature · 2008 · 6.4K citations · Full text

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Melatonin attenuates myocardial ischemia‐reperfusion injury via improving mitochondrial fusion/mitophagy and activating the AMPK‐OPA1 signaling pathways

Ying Zhang, Yue Wang, Junnan Xu et al. · Journal of Pineal Research · 2018 · 388 citations

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Insufficient autophagy in idiopathic pulmonary fibrosis

Jun Araya, Jun Kojima, Naoki Takasaka et al. · American Journal of Physiology-Lung Cellular and Molecular Physiology · 2012 · 326 citations

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RAS and RHO Families of GTPases Directly Regulate Distinct Phosphoinositide 3-Kinase Isoforms

Ralph Fritsch, Inge de Krijger, Kornelia Fritsch et al. · Cell · 2013 · 302 citations · Full text

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MTORC1 coordinates the autophagy and apoptosis signaling in articular chondrocytes in osteoarthritic temporomandibular joint

Hongxu Yang, Yi Wen, Mian Zhang et al. · Autophagy · 2019 · 297 citations · Full text

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