Emergence of a clinical isolate of E. coil ST297 co-carrying blaNDM-13 and mcr-1.1 in China

Abstract

To our knowledge, this is the first report of the coexistence of the IncI2 plasmid carrying mcr-1.1 and a bla_NDM-13-carrying integrated IncFIB/IncFII plasmid in an ST297 clinical E. coli isolate. In addition, we investigated a novel plasmid carrying bla_NDM-13. Our study expands the diversity of plasmids carrying bla_NDM-13, which exhibits epidemic importance in bacterial resistance. Therefore, there are important measures that should be taken to prevent the spread of these plasmids.