Investigating the biocompatibility, flexural strength, and surface roughness of denture base resin containing copper oxide nanoparticles: An in vitro study

Abstract

The CuO NPs were cytotoxic only when applied in high concentrations, but presented a descending trend over time. No cytotoxic effect was observed in the experimental groups after seven days of incubation. Furthermore, CuO NPs increased flexural strength, but the surface roughness of the PMMA discs was not affected.