Exosome-derived miR-372-5p promotes stemness and metastatic ability of CRC cells by inducing macrophage polarization

CAFs secreted exosomes promote metastasis and chemotherapy resistance by enhancing cell stemness and epithelial-mesenchymal transition in colorectal cancer

Jinwei Hu, Wei Wang, Xiao-Liang Lan et al. · Molecular Cancer · 2019 · 811 citations · Full text

Medicine, Cell Biology, Oncology +17

Cancer-Derived Succinate Promotes Macrophage Polarization and Cancer Metastasis via Succinate Receptor

Jing-Yiing Wu, Tsai‐Wang Huang, Yi‐Ting Hsieh et al. · Molecular Cell · 2019 · 529 citations · Full text

Medicine, Cancer Biology, Oncology +16

Exosome-encapsulated miRNAs contribute to CXCL12/CXCR4-induced liver metastasis of colorectal cancer by enhancing M2 polarization of macrophages

Dong Wang, Xiaohui Wang, Mahan Si et al. · Cancer Letters · 2020 · 422 citations

Medicine, Cancer Biology, Oncology +17

TM4SF1 promotes EMT and cancer stemness via the Wnt/β-catenin/SOX2 pathway in colorectal cancer

Qiang Tang, Jinhuang Chen, Ziyang Di et al. · Journal of Experimental & Clinical Cancer Research · 2020 · 352 citations · Full text

Medicine, Molecular Biology, Oncology +17

5-FU promotes stemness of colorectal cancer via p53-mediated WNT/β-catenin pathway activation

Yong‐Hee Cho, Eun Ji Ro, Jeong-Su Yoon et al. · Nature Communications · 2020 · 344 citations · Full text

Medicine, Oncology, Pharmacology +17