Xuebijing alleviates LPS-induced acute lung injury by downregulating pro-inflammatory cytokine production and inhibiting gasdermin-E-mediated pyroptosis of alveolar epithelial cells

TCMSP: a database of systems pharmacology for drug discovery from herbal medicines

Jinlong Ru, Peng Li, Jinan Wang et al. · Journal of Cheminformatics · 2014 · 5K citations · Full text

Medicine, Pharmacology, Bioavailability +16

ACUTE RESPIRATORY DISTRESS IN ADULTS

D G Ashbaugh, D. Boyd Bigelow, ThomasL. Petty · The Lancet · 1967 · 4.3K citations

Medicine, Internal Medicine, Radiology +13

Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin

Yupeng Wang, Wenqing Gao, Xuyan Shi et al. · Nature · 2017 · 3.2K citations

Life Sciences, Cell Biology, Oncology +13

Synergism of TNF-α and IFN-γ Triggers Inflammatory Cell Death, Tissue Damage, and Mortality in SARS-CoV-2 Infection and Cytokine Shock Syndromes

Rajendra Karki, Bhesh Raj Sharma, Shraddha Tuladhar et al. · Cell · 2020 · 1.7K citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +16

Caspase-8 induces cleavage of gasdermin D to elicit pyroptosis during <i>Yersinia</i> infection

Joseph Sarhan, Beiyun C. Liu, Hayley I. Muendlein et al. · Proceedings of the National Academy of Sciences · 2018 · 895 citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +15