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IQGAP1 promotes mitochondrial damage and activation of the mtDNA sensor cGAS-STING pathway to induce endothelial cell pyroptosis leading to atherosclerosis

InflammationMitochondrial DamageEndothelial Cell PyroptosisMitochondrial FunctionCell SignalingLipid PeroxidationPhysiologyVascular BiologyMedicineCell BiologyAtherosclerosisOxidative Stress