FOXQ1 inhibits breast cancer ferroptosis and progression via the circ_0000643/miR-153/SLC7A11 axis

The circRNA circSEPT9 mediated by E2F1 and EIF4A3 facilitates the carcinogenesis and development of triple-negative breast cancer

Xiaying Zheng, Mengge Huang, Lei Xing et al. · Molecular Cancer · 2020 · 522 citations · Full text

Medicine, Molecular Biology, Oncology +14

PARP inhibition promotes ferroptosis via repressing SLC7A11 and synergizes with ferroptosis inducers in BRCA-proficient ovarian cancer

Ting Hong, Guang Lei, Xue Chen et al. · Redox Biology · 2021 · 410 citations · Full text

Medicine, Oncology, Pharmacology +17

Metformin induces Ferroptosis by inhibiting UFMylation of SLC7A11 in breast cancer

Jingjing Yang, Yulu Zhou, Shuduo Xie et al. · Journal of Experimental & Clinical Cancer Research · 2021 · 379 citations · Full text

Medicine, Oncology, Pharmacology +17

SLC7A11/xCT in cancer: biological functions and therapeutic implications.

Wenyu Lin, Chaoqun Wang, Guangping Liu et al. · PubMed · 2020 · 272 citations · Full text

Medicine, Cancer Biology, Oncology +14

Circular RNA CRIM1 functions as a ceRNA to promote nasopharyngeal carcinoma metastasis and docetaxel chemoresistance through upregulating FOXQ1

Xiao-Hong Hong, Na Liu, Ye‐Lin Liang et al. · Molecular Cancer · 2020 · 254 citations · Full text

Medicine, Molecular Biology, Oncology +17