Concepedia

Metformin alleviates glucolipotoxicity-induced pancreatic β cell ferroptosis through regulation of the GPX4/ACSL4 axis

Yue Sun, Liqun Guo, Deguo Wang, Yujie Xing, Ya-Ping Bai, Teng Zhang, Wen Wang, Xin-ming Yao, Jinhan Cheng, Weiwei Chang,

European Journal of Pharmacology · 2023 · 28 citations · 21 references

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21

ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition

Sebastian Doll, Bettina Proneth, Yulia Y. Tyurina et al. · Nature Chemical Biology · 2016 · 4.1K citations · Full text

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ROS-mediated autophagy increases intracellular iron levels and ferroptosis by ferritin and transferrin receptor regulation

Eunhee Park, Su Wol Chung · Cell Death and Disease · 2019 · 881 citations · Full text

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Quercetin Alleviates Ferroptosis of Pancreatic β Cells in Type 2 Diabetes

Dan Li, Chunjie Jiang, Guibin Mei et al. · Nutrients · 2020 · 279 citations · Full text

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Metformin attenuates hyperlipidaemia-associated vascular calcification through anti-ferroptotic effects

Wenqi Ma, Xuejiao Sun, Yi Zhu et al. · Free Radical Biology and Medicine · 2021 · 164 citations

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The central role of glutathione peroxidase 4 in the regulation of ferroptosis and its implications for pro-inflammatory cytokine-mediated beta-cell death

B Krümmel, Thomas Plötz, Anne Jörns et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 2021 · 108 citations

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