Concepedia

What are the treatment remission, response and extent of improvement rates after up to four trials of antidepressant therapies in real-world depressed patients? A reanalysis of the STAR*D study’s patient-level data with fidelity to the original research protocol

H. Edmund Pigott, Thomas T. Kim, Colin Xu, Irving Kirsch, Jay D. Amsterdam

BMJ Open · 2023 · 63 citations · 28 references

DOIFull text

Open access

Abstract

STAR*D's cumulative remission rate was approximately half of that reported.

References

28

Acute and Longer-Term Outcomes in Depressed Outpatients Requiring One or Several Treatment Steps: A STAR*D Report

A. John Rush, Madhukar H. Trivedi, Stephen R. Wisniewski et al. · American Journal of Psychiatry · 2006 · 5.3K citations

Evaluation of Outcomes With Citalopram for Depression Using Measurement-Based Care in STAR*D: Implications for Clinical Practice

Madhukar H. Trivedi, A. John Rush, Stephen R. Wisniewski et al. · American Journal of Psychiatry · 2006 · 3.8K citations

The 16-Item quick inventory of depressive symptomatology (QIDS), clinician rating (QIDS-C), and self-report (QIDS-SR): a psychometric evaluation in patients with chronic major depression

A. John Rush, Madhukar H. Trivedi, Hicham M. Ibrahim et al. · Biological Psychiatry · 2003 · 3.8K citations

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Sequenced treatment alternatives to relieve depression (STAR*D): rationale and design

A. John Rush, Maurizio Fava, Stephen R. Wisniewski et al. · Controlled Clinical Trials · 2004 · 1.1K citations

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Bupropion-SR, Sertraline, or Venlafaxine-XR after Failure of SSRIs for Depression

A. John Rush, Madhukar H. Trivedi, Stephen R. Wisniewski et al. · New England Journal of Medicine · 2006 · 1K citations · Full text