Concepedia

Selective <i>N</i>-α-C–H alkylation of cyclic tertiary amides <i>via</i> visible-light-mediated 1,5-hydrogen atom transfer

Junlei Wang, Qinglin Xie, Guocheng Gao, Hongqing Li, Wenyun Lu, Xiaodong Cai, Xue‐Mei Chen, Binbin Huang

Organic Chemistry Frontiers · 2023 · 36 citations · 43 references

DOI

Concepts

Abstract

Herein, we report an effective C–H bond activation-alkylation strategy for 2-iodobenzoyl protected cyclic amines at the N -α-position through a visible-light mediated 1,5-hydrogen atom transfer (HAT) process.

References

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