Concepedia

A distinct cytokine network distinguishes chimeric antigen receptor T cell (CAR-T)–associated hemophagocytic lymphohistiocytosis-like toxicity (carHLH) from severe cytokine release syndrome following CAR-T therapy

Cheng Zu, Shenghao Wu, Mingming Zhang, Guoqing Wei, Huijun Xu, Jiazhen Cui, Alex H. Chang, He Huang, Yongxian Hu

Cytotherapy · 2023 · 22 citations · 18 references

DOI

Concepts

References

18

Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia

David Porter, Wei‐Ting Hwang, Noelle V. Frey et al. · Science Translational Medicine · 2015 · 1.7K citations · Full text

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A multicentre, randomised, double-blind, placebo-controlled trial with the interleukin-1 receptor antagonist anakinra in patients with systemic-onset juvenile idiopathic arthritis (ANAJIS trial)

Pierre Quartier, Florence Allantaz, Rolando Cimaz et al. · Annals of the Rheumatic Diseases · 2010 · 549 citations · Full text

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Longitudinal COVID-19 profiling associates IL-1RA and IL-10 with disease severity and RANTES with mild disease

Yan Zhao, Ling Qin, Ping Zhang et al. · JCI Insight · 2020 · 435 citations · Full text

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Benefit of Anakinra in Treating Pediatric Secondary Hemophagocytic Lymphohistiocytosis

Esraa M. Eloseily, Peter Weiser, Courtney B. Crayne et al. · Arthritis & Rheumatology · 2019 · 280 citations

, , +8

Characterization of HLH-like manifestations as a CRS variant in patients receiving CD22 CAR T cells

Daniel A. Lichtenstein, Fiorella Schischlik, Lipei Shao et al. · Blood · 2021 · 189 citations · Full text

, , +11