Trofinetide: a pioneering treatment for Rett syndrome

Trofinetide for the treatment of Rett syndrome: a randomized phase 3 study

Jeffrey L. Neul, Alan K. Percy, Tim A. Benke et al. · Nature Medicine · 2023 · 186 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +11

Illness Severity, Social and Cognitive Ability, and EEG Analysis of Ten Patients with Rett Syndrome Treated with Mecasermin (Recombinant Human IGF-1)

Giorgio Pini, L Congiu, Alberto Benincasa et al. · Autism Research and Treatment · 2016 · 52 citations · Full text

Medicine, Neurobiology, Neuroscience +17

Mechanism of Action for NNZ-2566 Anti-inflammatory Effects Following PBBI Involves Upregulation of Immunomodulator ATF3

Casandra M. Cartagena, Katie Phillips, Garry L. Williams et al. · NeuroMolecular Medicine · 2013 · 35 citations · Full text

Life Sciences, Immunology, Molecular Biology +14

MeCP2 deficiency exacerbates the neuroinflammatory setting and autoreactive response during an autoimmune challenge

María Inés Zalosnik, María Carolina Fabio, M. L. Bertoldi et al. · Scientific Reports · 2021 · 25 citations · Full text

Life Sciences, Immunology, Neuroscience +17

IGF-1 deficiency causes atrophic changes associated with upregulation of VGluT1 and downregulation of MEF2 transcription factors in the mouse cochlear nuclei

Verónica Fuentes‐Santamaría, Juan Carlos Alvarado, Lourdes Rodríguez‐de la Rosa et al. · Brain Structure and Function · 2014 · 17 citations

Life Sciences, Genetics, Molecular Biology +11