Concepedia

Garlic-derived exosome-like nanovesicles alleviate dextran sulphate sodium-induced mouse colitis <i>via</i> the TLR4/MyD88/NF-κB pathway and gut microbiota modulation

Zhenzhu Zhu, Liuyue Liao, Mingwei Gao, Qin Liu

Food & Function · 2023 · 105 citations · 28 references

DOI

Concepts

Abstract

. Totally, GENs had potential to protect the colon against DSS-induced damage through inhibiting the TLR4/MyD88/NF-κB signaling pathway and regulating gut microbiota. This study clarified the role of miRNAs of GENs in anti-colitis and proved that GENs had a potential application for IBD prevention.

References

28

The microRNA Registry

Sam Griffiths‐Jones · Nucleic Acids Research · 2003 · 2.2K citations · Full text

, , +17

Plant-Derived Exosomal MicroRNAs Shape the Gut Microbiota

Yun Teng, Yi Ren, Mohammed Sayed et al. · Cell Host & Microbe · 2018 · 974 citations · Full text

, , +16

Interspecies communication between plant and mouse gut host cells through edible plant derived exosome‐like nanoparticles

Jingyao Mu, Xiaoying Zhuang, Qilong Wang et al. · Molecular Nutrition & Food Research · 2014 · 700 citations · Full text

, , +12

Reconstruction of LPS Transfer Cascade Reveals Structural Determinants within LBP, CD14, and TLR4-MD2 for Efficient LPS Recognition and Transfer

Je‐Kyung Ryu, Soo Jin Kim, Sang-Hyun Rah et al. · Immunity · 2016 · 434 citations · Full text

, , +12

Integrative analysis of the microbiome and metabolome of the human intestinal mucosal surface reveals exquisite inter-relationships

Ian McHardy, Maryam Goudarzi, Maomeng Tong et al. · Microbiome · 2013 · 335 citations · Full text

, , +17