Targeted nanodelivery of siRNA against KRAS G12D inhibits pancreatic cancer

Cancer statistics, 2022

Rebecca L. Siegel, Kimberly D. Miller, Hannah E. Fuchs et al. · CA A Cancer Journal for Clinicians · 2022 · 18.2K citations · Full text

Medicine, Oncology, Cancer Epidemiology +16

Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer

Sushrut Kamerkar, Valerie S. LeBleu, Hikaru Sugimoto et al. · Nature · 2017 · 2.6K citations

Medicine, Cancer Biology, Oncology +13

KRAS ^G12C Inhibition with Sotorasib in Advanced Solid Tumors

David S. Hong, Marwan Fakih, John H. Strickler et al. · New England Journal of Medicine · 2020 · 1.7K citations · Full text

Medicine, Oncology, Oncogenes +1

Anti-tumor efficacy of a potent and selective non-covalent KRASG12D inhibitor

Jill Hallin, Vickie Bowcut, Andrew Calinisan et al. · Nature Medicine · 2022 · 507 citations

Medicine, Medicinal Chemistry, Oncology +9

Effect of ligand density, receptor density, and nanoparticle size on cell targeting

Drew R. Elias, Andrei Poloukhtine, Vladimir V. Popik et al. · Nanomedicine Nanotechnology Biology and Medicine · 2012 · 390 citations

Pharmacy, Cell Biology, Pharmaceutics +14