Concepedia

Upadacitinib Salvage Therapy for Infliximab-Experienced Patients with Acute Severe Ulcerative Colitis

Robert Gilmore, Wei Lian Tan, Richard Fernandes, Yoon‐Kyo An, Jakob Begun

Journal of Crohn s and Colitis · 2023 · 53 citations · 6 references

DOIFull text

Open access

Abstract

Upadacitinib may have a role as a safe and effective salvage therapy for steroid-refractory ASUC in patients who have previously failed to respond to infliximab therapy. Prospective studies are required to determine the safety and efficacy of upadacitinib use in this setting before routine use can be recommended.

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